INTRODUCTION: This study aims to compare the effectiveness of topical nasal steroids for nasal obstruction symptoms between advanced age patients and young-middle age patients based on acoustic rhinometry values and correlations with mucociliary clearance.
METHODS: Our study population consisted of 27 advanced aged patients (15 males, 12 females; mean age 67 years; range, 65 to 76) (group 1) and 36 young-middle aged patients (20 males, 16 females; mean age 36.1 years; range, 15 to 49 years) (group 2). Patients with a history of allergic rhinitis (AR) with positive skin prick tests were referred from the Department of Respiratory Medicine. All patients were evaluated with objective and subjective methods before and after using topical nasal steroids for six weeks. We used rhinometric evaluation and saccharin test as objective methods and assessed patients with nasal obstruction symptom evaluation (NOSE) and visual analog scale (VAS) as subjective methods.
RESULTS: Baseline subjective scores of group 1 were significantly lower than group 2 (p<0.05). Percent change of VAS and NOSE scores were markedly higher in group 2 compared to group 1 (p<0.05). There was no significant difference between groups in terms of the change in saccharin time following nasal steroid treatment (p>0.05). Baseline total minimum cross-sectional area (MCA3) and total volume of nasal cavity (VOL3) values of group 1 were significantly higher than group 2 (p<0.05). The change of MCA3 and VOL3 values did not differ between the groups before and after treatment with nasal steroids (p>0.05).
DISCUSSION AND CONCLUSION: In this study, we have shown that the elderly have reduced awareness of their nasal symptoms of AR. We have demonstrated that topical treatment with nasal steroids was more effective in the young-middle age group subjectively.