INTRODUCTION: This study aims to evaluate demographic characteristics, tumor characteristics, and survival outcomes of surgically treated patients with oral cavity cancer (OCC).
METHODS: A total of 459 OCC patients (269 males, 190 females; mean age 61.4±15.0 years; range, 18 to 90 years) who were treated with surgery between January 2000 and December 2015 were retrospectively analyzed. Demographic data, diagnosis, histopathological type, tumor origin, tumor stage, neck status, type of surgery, reconstruction technique, complications, follow-up duration, recurrence, and survival status were recorded.
RESULTS: The tumor originated from the lip in 134 (29.2%) of the patients. The histopathological diagnosis was a squamous cell carcinoma in 403 patients (87.8%). The five-year overall survival and disease-free survival rates were 69.5% and 60.8%, respectively. The five-year overall survival rate was significantly lower in patients with neck metastasis (p<0.05).
DISCUSSION AND CONCLUSION: Our study results suggest that regional lymph node metastasis, age, and surgical margin are the main factors affecting survival and prognosis in OCC.